Histone Methylation-Dependent Mechanisms Impose Ligand Dependency for Gene Activation by Nuclear Receptors

Nuclear receptors undergo ligand-dependent conformational changes that are required for corepressor-coactivator exchange, but whether there is an actual requirement for specific epigenetic landmarks to impose ligand dependency for gene activation remains unknown. Here we report an unexpected and gen...

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Detalhes bibliográficos
Main Authors: Garcia-Bassets, Ivan, Kwon, Young-Soo, Telese, Francesca, Prefontaine, Gratien G., Hutt, Kasey R., Cheng, Christine S., Ju, Bong-Gun, Ohgi, Kenneth A., Wang, Jianxun, Escoubet-Lozach, Laure, Rose, David W., Glass, Christopher K., Fu, Xiang-Dong, Rosenfeld, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994663/
https://ncbi.nlm.nih.gov/pubmed/17289570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.12.038
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