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Modulation of Aire regulates the expression of tissue-restricted antigens

Intrathymic expression of tissue-restricted antigens (TRAs) has been viewed as the key element in the induction of central tolerance and recently, a central role for the autoimmune regulator (Aire) has been suggested in this process. The aim of this study was to establish whether down or up-regulati...

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Autors principals: Kont, Vivian, Laan, Martti, Kisand, Kai, Merits, Andres, Scott, Hamish S., Peterson, Pärt
Format: Artigo
Idioma:Inglês
Publicat: Pergamon Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994210/
https://ncbi.nlm.nih.gov/pubmed/17599412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.05.014
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