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Crystal structure of pyruvate dehydrogenase phosphatase 1 and its functional implications

Pyruvate dehydrogenase phosphatase 1 (PDP1) catalyzes dephosphorylation of pyruvate dehydrogenase (E1) in the mammalian pyruvate dehydrogenase complex (PDC) whose activity is regulated by the phosphorylation-dephosphorylation cycle by the corresponding protein kinases (PDHKs) and phosphatases. The a...

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Detalhes bibliográficos
Main Authors: Vassylyev, Dmitry G., Symersky, Jindrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994205/
https://ncbi.nlm.nih.gov/pubmed/17532339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.05.002
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