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Poliovirus entry into human brain microvascular cells requires receptor-induced activation of SHP-2

Viruses use specific receptor molecules to bind selectively to target cells. Receptors have often been considered as mere docking sites, but they may also possess intrinsic signaling capacities that serve to prime the cell for entry and infection. Poliovirus (PV) initiates infection by binding to th...

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Detalhes bibliográficos
Principais autores: Coyne, Carolyn B, Kim, Kwang S, Bergelson, Jeffrey M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994131/
https://ncbi.nlm.nih.gov/pubmed/17717529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601831
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