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PocketPicker: analysis of ligand binding-sites with shape descriptors

BACKGROUND: Identification and evaluation of surface binding-pockets and occluded cavities are initial steps in protein structure-based drug design. Characterizing the active site's shape as well as the distribution of surrounding residues plays an important role for a variety of applications s...

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Bibliografische gegevens
Hoofdauteurs: Weisel, Martin, Proschak, Ewgenij, Schneider, Gisbert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994066/
https://ncbi.nlm.nih.gov/pubmed/17880740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-153X-1-7
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