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High yield, purity and activity of soluble recombinant Bacteroides thetaiotaomicron GST-heparinase I from Escherichia coli*

Heparinase I from Flavobacterium heparinum, a source of diverse polysaccharidases, suffers from low yields, insufficient purity for structural studies and insolubility when expressed as a recombinant product in Escherichia coli that is devoid of glycosaminoglycan polysaccharidases. In this study, cD...

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Main Authors: Luo, Yongde, Huang, Xinqiang, McKeehan, Wallace L.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993911/
https://ncbi.nlm.nih.gov/pubmed/17346663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.01.029
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