Cervical keratinocytes containing stably replicating extrachromosomal HPV-16 are refractory to transformation by oncogenic H-Ras

Ras expression in human epithelial cells with integrated HPV genomes has been shown to cause tumorigenic transformation. The effects of Ras in cells representing early stage HPV-associated disease (i.e., when HPV is extrachromosomal and the oncogenes are under control of native promoters) have not b...

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Autores principales: Berger, Kristi L., Barriga, Felicia, Lace, Michael J., Turek, Lubomir P., Zamba, Gideon J., Domann, Frederick E., Lee, John H., Klingelhutz, Aloysius J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993897/
https://ncbi.nlm.nih.gov/pubmed/16945398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.07.039
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