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Cro’s role in the CI–Cro bistable switch is critical for λ’s transition from lysogeny to lytic development

CI represses cro; Cro represses cI. This double negative feedback loop is the core of the classical CI–Cro epigenetic switch of bacteriophage λ. Despite the classical status of this switch, the role in λ development of Cro repression of the P(RM) promoter for CI has remained unclear. To address this...

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Bibliografiske detaljer
Main Authors: Schubert, Rachel A., Dodd, Ian B., Egan, J. Barry, Shearwin, Keith E.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993876/
https://ncbi.nlm.nih.gov/pubmed/17908932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1584907
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