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A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori’s disease

Cori’s disease is a glycogen storage disorder characterized by a deficiency in the glycogen debranching enzyme, amylo-1,6-glucosidase,4-α-glucanotransferase (AGL). Here, we demonstrate that the G1448R genetic variant of AGL is unable to bind to glycogen and displays decreased stability that is rescu...

詳細記述

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書誌詳細
主要な著者: Cheng, Alan, Zhang, Mei, Gentry, Matthew S., Worby, Carolyn A., Dixon, Jack E., Saltiel, Alan R.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993871/
https://ncbi.nlm.nih.gov/pubmed/17908927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1553207
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