A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori’s disease

Cori’s disease is a glycogen storage disorder characterized by a deficiency in the glycogen debranching enzyme, amylo-1,6-glucosidase,4-α-glucanotransferase (AGL). Here, we demonstrate that the G1448R genetic variant of AGL is unable to bind to glycogen and displays decreased stability that is rescu...

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Bibliographic Details
Main Authors: Cheng, Alan, Zhang, Mei, Gentry, Matthew S., Worby, Carolyn A., Dixon, Jack E., Saltiel, Alan R.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1993871/
https://ncbi.nlm.nih.gov/pubmed/17908927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1553207
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