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BDA-410: A novel synthetic calpain inhibitor active against blood stage malaria
Falcipains, the papain-family cysteine proteases of the Plasmodium falciparum, are potential drug targets for malaria parasite. Pharmacological inhibition of falcipains can block the hydrolysis of hemoglobin, parasite development, and egress, suggesting that falcipains play a key role at the blood s...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1993804/ https://ncbi.nlm.nih.gov/pubmed/17583361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2007.05.004 |
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