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An X chromosome gene regulates hematopoietic stem cell kinetics

Females are natural mosaics for X chromosome-linked genes. As X chromosome inactivation occurs randomly, the ratio of parental phenotypes among blood cells is approximately 1:1. Recently, however, ratios of greater than 3:1 have been observed in 38–56% of women over age 60. This could result from a...

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Detalhes bibliográficos
Main Authors: Abkowitz, Janis L., Taboada, Monica, Shelton, Grady H., Catlin, Sandra N., Guttorp, Peter, Kiklevich, J. Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19928/
https://ncbi.nlm.nih.gov/pubmed/9520458
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