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The kinetics of clonal dominance in myeloproliferative disorders

To study clonal evolution in myeloproliferative disorders, we used stochastic models of hematopoiesis for mouse and cat, species for which the in vivo kinetics of hematopoietic stem cells (HSCs) have been experimentally defined. We determined the consequence if 1 HSC became able to survive without t...

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Autori principali: Catlin, Sandra N., Guttorp, Peter, Abkowitz, Janis L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Hematology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895315/
https://ncbi.nlm.nih.gov/pubmed/16002428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1240
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