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In vivo selection for the directed evolution of L-rhamnulose aldolase from L-rhamnulose-1-phosphate aldolase (RhaD)

Dihydroxyacetone phosphate (DHAP) dependent aldolases have been widely used for organic synthesis. The major drawback of DHAP-dependent aldolases is their strict donor substrate specificity toward DHAP, which is expensive and unstable. Here we report the development of an in vivo selection system fo...

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Bibliografske podrobnosti
Main Authors: Sugiyama, Masakazu, Hong, Zhangyong, Greenberg, William A., Wong, Chi-Huey
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1992742/
https://ncbi.nlm.nih.gov/pubmed/17572092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.05.062
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