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Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients

CD4 T-cell help is required during the generation and maintenance of effective antitumor CD8 T cell–mediated immunity. The goal of this study was to determine whether HER-2/neu–specific CD8 T-cell immunity could be elicited using HER-2/neu–derived MHC class II “helper” peptides, which contain encomp...

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Библиографические подробности
Главные авторы: Knutson, Keith L., Schiffman, Kathy, Disis, Mary L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2001
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC199268/
https://ncbi.nlm.nih.gov/pubmed/11181647
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