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IFN-γ–dependent transcription of MHC class II IA is impaired in macrophages from aged mice

To determine the effect of aging on IFN-γ–induced MHC class II antigen expression, we produced bone marrow–derived macrophages in vitro. In these conditions, we analyzed the effect of aging on the genomic expression of macrophages without the influence of other cell types that may be affected by agi...

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Detaylı Bibliyografya
Asıl Yazarlar: Herrero, Carmen, Marqués, Laura, Lloberas, Jorge, Celada, Antonio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC199261/
https://ncbi.nlm.nih.gov/pubmed/11181648
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