Altered T cell development in human thymoma is related to impairment of MHC class II transactivator expression induced by interferon-gamma (IFN-γ)

Thymoma is known to contain CD4(+)CD8(+) T cells, indicating that neoplastic epithelial cells of thymoma have a function as thymic cortical epithelium. However, it has been shown that there is an impairment of CD4(+) T cell development in thymoma and that IFN-γ-induced HLA-DR expression on cultured...

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Main Authors: Kadota, Y, Okumura, M, Miyoshi, S, Kitagawa-Sakakida, S, Inoue, M, Shiono, H, Maeda, Y, Kinoshita, T, Shirakura, R, Matsuda, H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Cancer Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905672/
https://ncbi.nlm.nih.gov/pubmed/10886240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01256.x
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