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Alteration of Drosophila life span using conditional, tissue-specific expression of transgenes triggered by doxycycline or RU486/Mifepristone

The conditional systems Tet-on and Geneswitch were compared and optimized for the tissue-specific expression of transgenes and manipulation of life span in adult Drosophila. Two versions of Tet-on system reverse-tetracycline-Trans-Activator (rtTA) were compared: the original rtTA, and rtTAM2-alt con...

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Main Authors: Ford, Daniel, Hoe, Nicholas, Landis, Gary N., Tozer, Kevin, Luu, Allan, Bhole, Deepak, Badrinath, Ananth, Tower, John
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1992522/
https://ncbi.nlm.nih.gov/pubmed/17349761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2007.01.004
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