Increased atherosclerosis in myeloperoxidase-deficient mice

Myeloperoxidase (MPO), a heme enzyme secreted by activated phagocytes, generates an array of oxidants proposed to play critical roles in host defense and local tissue damage. Both MPO and its reaction products are present in human atherosclerotic plaque, and it has been proposed that MPO oxidatively...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Brennan, Marie-Luise, Anderson, Melissa M., Shih, Diana M., Qu, Xiao-Dan, Wang, Xuping, Mehta, Asha C., Lim, Lesley L., Shi, Weibin, Hazen, Stanley L., Jacob, Jason S., Crowley, Jan R., Heinecke, Jay W., Lusis, Aldons J.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 2001
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC199241/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11181641/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8797
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