Increased atherosclerosis in myeloperoxidase-deficient mice

Myeloperoxidase (MPO), a heme enzyme secreted by activated phagocytes, generates an array of oxidants proposed to play critical roles in host defense and local tissue damage. Both MPO and its reaction products are present in human atherosclerotic plaque, and it has been proposed that MPO oxidatively...

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Autors principals: Brennan, Marie-Luise, Anderson, Melissa M., Shih, Diana M., Qu, Xiao-Dan, Wang, Xuping, Mehta, Asha C., Lim, Lesley L., Shi, Weibin, Hazen, Stanley L., Jacob, Jason S., Crowley, Jan R., Heinecke, Jay W., Lusis, Aldons J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2001
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC199241/
https://ncbi.nlm.nih.gov/pubmed/11181641
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