Haemoglobin C and S Role in Acquired Immunity against Plasmodium falciparum Malaria

A recently proposed mechanism of protection for haemoglobin C (HbC; β6Glu→Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced cytoadhesion of parasitized erythrocytes and impaired...

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Dettagli Bibliografici
Autori principali: Verra, Federica, Simpore, Jacques, Warimwe, George M., Tetteh, Kevin K., Howard, Tevis, Osier, Faith H. A., Bancone, Germana, Avellino, Pamela, Blot, Isa, Fegan, Greg, Bull, Peter C., Williams, Thomas N., Conway, David J., Marsh, Kevin, Modiano, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991593/
https://ncbi.nlm.nih.gov/pubmed/17912355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000978
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