Haemoglobin C and S Role in Acquired Immunity against Plasmodium falciparum Malaria

A recently proposed mechanism of protection for haemoglobin C (HbC; β6Glu→Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced cytoadhesion of parasitized erythrocytes and impaired...

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Detalhes bibliográficos
Main Authors: Verra, Federica, Simpore, Jacques, Warimwe, George M., Tetteh, Kevin K., Howard, Tevis, Osier, Faith H. A., Bancone, Germana, Avellino, Pamela, Blot, Isa, Fegan, Greg, Bull, Peter C., Williams, Thomas N., Conway, David J., Marsh, Kevin, Modiano, David
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991593/
https://ncbi.nlm.nih.gov/pubmed/17912355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000978
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