Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme

QueF (MW = 19.4 kDa) is a recently characterized nitrile oxidoreductase which catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ(0)) to 7-aminomethyl-7-deazaguanine, a late step in the biosynthesis of the modified tRNA nucleoside queuosine. Initial crystals of homododecameric Ba...

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Bibliographic Details
Main Authors: Swairjo, Manal A., Reddy, Robert R., Lee, Bobby, Van Lanen, Steven G., Brown, Shannon, de Crécy-Lagard, Valérie, Iwata-Reuyl, Dirk, Schimmel, Paul
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2005
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991305/
https://ncbi.nlm.nih.gov/pubmed/16511203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105029246
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