Incorporation of a disaccharide nucleoside into the backbone of double-stranded DNA: crystallization and preliminary X-ray diffraction

Incorporation of a disaccharide nucleoside into double-stranded DNA can be considered as a chemical (non-enzymatic) alternative for site-specific cleavage of DNA. Crystals of the sequence d(CGCGAATT*CGCG), where * is an incorporated ribose, were obtained by hanging-drop vapour diffusion and diffract...

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Bibliographic Details
Main Authors: Van Hecke, Kristof, Uytterhoeven, Koen, Mikhailov, Sergey N., Herdewijn, Piet, Van Meervelt, Luc
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2005
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991303/
https://ncbi.nlm.nih.gov/pubmed/16511205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309105030381
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