The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice

Members of the transforming growth factor (TGF)-β superfamily have been shown to play a variety of important roles in embryogenesis, including dorsal and ventral mesoderm induction. The tumor suppressor SMAD4, also known as DPC4, is believed to be an essential factor that mediates TGF-β signals. To...

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Библиографические подробности
Главные авторы: Yang, Xiao, Li, Cuiling, Xu, Xiaoling, Deng, Chuxia
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1998
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC19893/
https://ncbi.nlm.nih.gov/pubmed/9520423
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