Germ Line Origin and Somatic Mutations Determine the Target Tissues in Systemic AL-Amyloidosis

BACKGROUND: Amyloid is insoluble aggregated proteins deposited in the extra cellular space. About 25 different proteins are known to form amyloid in vivo and are associated with severe diseases such as Alzheimeŕs disease, prion diseases and type-2 diabetes. Light chain (AL) -amyloidosis is unique am...

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Detaylı Bibliyografya
Asıl Yazarlar: Enqvist, Stina, Sletten, Knut, Stevens, Fred J., Hellman, Ulf, Westermark, Per
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1989140/
https://ncbi.nlm.nih.gov/pubmed/17912358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000981
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