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Packaging of intron-containing genes into retrovirus vectors by alphavirus vectors

Efficient and controllable expression of a transgene usually requires the presence of intron sequences and much efforts have been made to produce retrovirus vectors that can transduce and integrate genes with introns. However, this has proven difficult because the viral RNA is spliced when it is syn...

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Autori principali: Li, Ke-Jun, Garoff, Henrik
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC19890/
https://ncbi.nlm.nih.gov/pubmed/9520420
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