Radioiodide imaging and radiovirotherapy of multiple myeloma using VSV(Δ51)-NIS, an attenuated vesicular stomatitis virus encoding the sodium iodide symporter gene

Multiple myeloma is a radiosensitive malignancy that is currently incurable. Here, we generated a novel recombinant vesicular stomatitis virus [VSV(Δ51)-NIS] that has a deletion of methionine 51 in the matrix protein and expresses the human sodium iodide symporter (NIS) gene. VSV(Δ51)-NIS showed spe...

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Detalhes bibliográficos
Main Authors: Goel, Apollina, Carlson, Stephanie K., Classic, Kelly L., Greiner, Suzanne, Naik, Shruthi, Power, Anthony T., Bell, John C., Russell, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Gene Therapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988925/
https://ncbi.nlm.nih.gov/pubmed/17515401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-065573
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