Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis

Statins are a class of drugs that inhibit 3-hydroxy-3-methylglutaryl-coenzyme A (HMGcoA) reductase, a critical enzyme in the mevalonate pathway. Several reports document that statins may prevent different human cancers. However, whether or not statins can prevent cancer is controversial due to disco...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Shachaf, Catherine M., Perez, Omar D., Youssef, Sawsan, Fan, Alice C., Elchuri, Sailaja, Goldstein, Matthew J., Shirer, Amy E., Sharpe, Orr, Chen, Joy, Mitchell, Dennis J., Chang, Maria, Nolan, Garry P., Steinman, Lawrence, Felsher, Dean W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2007
Aiheet:
Neoplasia
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988916/
https://ncbi.nlm.nih.gov/pubmed/17622571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-09-048033
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