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Cloned mammalian neutral sphingomyelinase: Functions in sphingolipid signaling?

Sphingomyelin is an abundant constituent of the plasma membranes of mammalian cells. Ceramide, its primary catabolic intermediate, is released by either acid sphingomyelinase or neutral sphingomyelinase (nSMase) and has emerged as a potential lipid signaling molecule. nSMase is regarded as a key enz...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tomiuk, Stefan, Hofmann, Kay, Nix, Michael, Zumbansen, Markus, Stoffel, Wilhelm
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19888/
https://ncbi.nlm.nih.gov/pubmed/9520418
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