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A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration

Genetic variants at chromosomes 1q31-32 and 10q26 are strongly associated with susceptibility to age-related macular degeneration (AMD), a common blinding disease of the elderly. We demonstrate, by evaluating 45 tag SNPs spanning HTRA1, PLEKHA1, and predicted gene LOC387715/ARMS2, that rs10490924 SN...

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Detalhes bibliográficos
Main Authors: Kanda, Atsuhiro, Chen, Wei, Othman, Mohammad, Branham, Kari E. H., Brooks, Matthew, Khanna, Ritu, He, Shirley, Lyons, Robert, Abecasis, Gonçalo R., Swaroop, Anand
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987388/
https://ncbi.nlm.nih.gov/pubmed/17884985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703933104
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