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Biased clustered substitutions in the human genome: The footprints of male-driven biased gene conversion

We examined fixed substitutions in the human lineage since divergence from the common ancestor with the chimpanzee, and determined what fraction are AT to GC (weak-to-strong). Substitutions that are densely clustered on the chromosomes show a remarkable excess of weak-to-strong “biased” substitution...

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Bibliographic Details
Main Authors: Dreszer, Timothy R., Wall, Gregory D., Haussler, David, Pollard, Katherine S.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987345/
https://ncbi.nlm.nih.gov/pubmed/17785536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.6395807
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