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Acrolein induces selective protein carbonylation in synaptosomes

Acrolein, the most reactive of the α,β-unsaturated aldehydes, is endogenously produced by lipid peroxidation, and has been found increased in the brain of patients with Alzheimer's disease. Although it is known that acrolein increases total protein carbonylation and impairs the function of sele...

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Detalhes bibliográficos
Main Authors: Mello, C.F., Sultana, R., Piroddi, M., Cai, J., Pierce, W.M., Klein, J.B., Butterfield, D.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987324/
https://ncbi.nlm.nih.gov/pubmed/17570602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.04.003
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