A study of the relationship between the pharmacokinetics and the pharmacodynamics of the 4-hydroxycoumarin anticoagulants warfarin, difenacoum and brodifacoum in the rabbit.

The pharmacokinetics and pharmacodynamics of the 4-hydroxycoumarin anticoagulants, brodifacoum, difenacoum, and warfarin have been studied in the rabbit. Sensitive (50 ng ml-1) and specific high performance liquid chromatography assays have been developed for the determination of plasma concentratio...

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Hlavní autoři: Breckenridge, A. M., Cholerton, S., Hart, J. A., Park, B. K., Scott, A. K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1985
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987219/
https://ncbi.nlm.nih.gov/pubmed/3978316
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