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Is Ro 03-7894 an irreversible antagonist at beta-adrenoceptor sites?

Ro 03-7894 (0.6 mM) produced a non-parallel shift to the right of dose-response curves to (-)-isoprenaline in K+ depolarized uterine preparations from the guinea-pig. The displacement of the curves was readily reversed by washing. A rightward shift of similar magnitude was also produced by Ro 03-789...

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Hlavní autoři: Krstew, E., McPherson, G. A., Malta, E., Molenaar, P., Raper, C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1984
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987030/
https://ncbi.nlm.nih.gov/pubmed/6145474
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