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The affinity and efficacy of the selective beta 1-adrenoceptor stimulant RO363 at beta 1- and beta 2-adrenoceptor sites.

(-)-Isoprenaline and the selective beta 1-adrenoceptor agonist RO363 were tested for their inotropic effects in left atrial (beta 1) and relaxant effects in K+-depolarized uterine (beta 2) preparations from the guinea-pig. The drugs had similar activities as positive inotropic agents but RO363 was a...

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Autori principali: McPherson, G. A., Malta, E., Molenaar, P., Raper, C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1984
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986931/
https://ncbi.nlm.nih.gov/pubmed/6148117
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