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23S rRNA positions essential for tRNA binding in ribosomal functional sites

rRNA plays an important role in function of peptidyl transferase, the catalytic center of the ribosome responsible for the peptide bond formation. Proper placement of the peptidyl transferase substrates, peptidyl-tRNA and aminoacyl-tRNA, is essential for catalysis of the transpeptidation reaction an...

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Detalles Bibliográficos
Main Authors: Bocchetta, Maurizio, Xiong, Liqun, Mankin, Alexander S.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC19869/
https://ncbi.nlm.nih.gov/pubmed/9520399
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