A novel monoclonal antibody against human Argonaute proteins reveals unexpected characteristics of miRNAs in human blood cells

Argonaute (Ago) proteins bind to microRNA (miRNAs) and short interfering RNAs (siRNAs) and form the core components of effector complexes that mediate miRNA and siRNA function. Currently, there is a paucity of reliable antibodies against mammalian Ago proteins, thus precluding studies of endogenous...

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Main Authors: Nelson, Peter T., De Planell-Saguer, Mariangels, Lamprinaki, Stella, Kiriakidou, Marianthi, Zhang, Paul, O'Doherty, Una, Mourelatos, Zissimos
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2007
主題:
Method
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986805/
https://ncbi.nlm.nih.gov/pubmed/17720879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.646007
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