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A novel monoclonal antibody against human Argonaute proteins reveals unexpected characteristics of miRNAs in human blood cells

Argonaute (Ago) proteins bind to microRNA (miRNAs) and short interfering RNAs (siRNAs) and form the core components of effector complexes that mediate miRNA and siRNA function. Currently, there is a paucity of reliable antibodies against mammalian Ago proteins, thus precluding studies of endogenous...

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Detalhes bibliográficos
Main Authors: Nelson, Peter T., De Planell-Saguer, Mariangels, Lamprinaki, Stella, Kiriakidou, Marianthi, Zhang, Paul, O'Doherty, Una, Mourelatos, Zissimos
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986805/
https://ncbi.nlm.nih.gov/pubmed/17720879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.646007
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