COBALTOUS CHLORIDE AND HYPOXIA INHIBIT ARYL HYDROCARBON RECEPTOR-MEDIATED RESPONSES IN BREAST CANCER CELLS

The aryl hydrocarbon receptor (AhR) is expressed in estrogen receptor (ER)-positive ZR-75 breast cancer cells. Treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces CYP1A1 protein and mRNA levels and also activates inhibitory AhR-Erα crosstalk associated with hormone-induced reporter gen...

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Bibliographic Details
Main Authors: Khan, Shaheen, Liu, Shengxi, Stoner, Matthew, Safe, Stephen
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986799/
https://ncbi.nlm.nih.gov/pubmed/17599377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.05.010
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