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The Cellular Prion Protein (PrP(C)): Its Physiological Function and Role in Disease
Prion diseases are caused by conversion of a normal cell-surface glycoprotein (PrP(C)) into a conformationally altered isoform (PrP(Sc)) that is infectious in the absence of nucleic acid. Although a great deal has been learned about PrP(Sc) and its role in prion propagation, much less is known about...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1986710/ https://ncbi.nlm.nih.gov/pubmed/17451912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2007.02.011 |
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