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Identification of a transient excision intermediate at the crossroads between DNA polymerase extension and proofreading pathways

DNA polymerases achieve accurate DNA replication through a delicate balance between primer elongation and proofreading. While insufficient proofreading results in DNA replication errors, indiscriminate removal of correct along with incorrect nucleotides is wasteful and may prevent completion of DNA...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Baker, Rosanna P., Reha-Krantz, Linda J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1998
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19866/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520396/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3507
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