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Identification of a transient excision intermediate at the crossroads between DNA polymerase extension and proofreading pathways

DNA polymerases achieve accurate DNA replication through a delicate balance between primer elongation and proofreading. While insufficient proofreading results in DNA replication errors, indiscriminate removal of correct along with incorrect nucleotides is wasteful and may prevent completion of DNA...

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Détails bibliographiques
Auteurs principaux: Baker, Rosanna P., Reha-Krantz, Linda J.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC19866/
https://ncbi.nlm.nih.gov/pubmed/9520396
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