Gene rearrangement attenuates expression and lethality of a nonsegmented negative strand RNA virus
The nonsegmented negative strand RNA viruses comprise hundreds of human, animal, insect, and plant pathogens. Gene expression of these viruses is controlled by the highly conserved order of genes relative to the single transcriptional promoter. We utilized this regulatory mechanism to alter gene exp...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1998
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3501 |
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