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Control of zinc transfer between thionein, metallothionein, and zinc proteins

Metallothionein (MT), despite its high metal binding constant (K(Zn) = 3.2 × 10(13) M(−1) at pH 7.4), can transfer zinc to the apoforms of zinc enzymes that have inherently lower stability constants. To gain insight into this paradox, we have studied zinc transfer between zinc enzymes and MT. Zinc c...

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Autori principali: Jacob, Claus, Maret, Wolfgang, Vallee, Bert L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC19863/
https://ncbi.nlm.nih.gov/pubmed/9520393
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