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EBNA1-specific CD4(+) T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function

The Epstein-Barr virus (EBV) nuclear antigen-1 (EBNA1) maintains the viral episome in all host cells infected with EBV. Recently, EBNA1 was found to be the main EBV latency antigen for CD4(+) T cells and could be recognized in cultures from all donors tested. We now identify a polarized Th1 phenotyp...

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Bibliografiske detaljer
Main Authors: Bickham, Kara, Münz, Christian, Tsang, Ming Li, Larsson, Marie, Fonteneau, Jean-Francois, Bhardwaj, Nina, Steinman, Ralph
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC198542/
https://ncbi.nlm.nih.gov/pubmed/11134187
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