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Antigen therapy eliminates T cell inflammation by apoptosis: Effective treatment of experimental autoimmune neuritis with recombinant myelin protein P2

Exposure of T cells to their specific antigen normally results in proliferation, but in the presence of high and repeatedly administered doses of antigen, T cells may undergo apoptosis. Here we demonstrate that i.v. administration of as little as 100 μg of recombinant P2 protein twice daily complete...

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Detalhes bibliográficos
Main Authors: Weishaupt, Andreas, Gold, Ralf, Gaupp, Stefanie, Giegerich, Gerhard, Hartung, Hans-Peter, Toyka, Klaus V.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC19792/
https://ncbi.nlm.nih.gov/pubmed/9037054
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