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Constraint-Based Modeling and Kinetic Analysis of the Smad Dependent TGF-β Signaling Pathway

BACKGROUND: Investigation of dynamics and regulation of the TGF-β signaling pathway is central to the understanding of complex cellular processes such as growth, apoptosis, and differentiation. In this study, we aim at using systems biology approach to provide dynamic analysis on this pathway. METHO...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zi, Zhike, Klipp, Edda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978528/
https://ncbi.nlm.nih.gov/pubmed/17895977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000936
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