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Constraint-Based Modeling and Kinetic Analysis of the Smad Dependent TGF-β Signaling Pathway

BACKGROUND: Investigation of dynamics and regulation of the TGF-β signaling pathway is central to the understanding of complex cellular processes such as growth, apoptosis, and differentiation. In this study, we aim at using systems biology approach to provide dynamic analysis on this pathway. METHO...

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Библиографические подробности
Главные авторы: Zi, Zhike, Klipp, Edda
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978528/
https://ncbi.nlm.nih.gov/pubmed/17895977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000936
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