In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands

BACKGROUND AND PURPOSE: We have previously reported the development of CB-25 and CB-52, two ligands of CB(1) and CB(2) cannabinoid receptors. We assessed here their functional activity. EXPERIMENTAL APPROACH: The effect of the two compounds on forskolin-induced cAMP formation in intact cells or GTP-...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Cascio, M G, Bisogno, T, Palazzo, E, Thomas, A, van der Stelt, M, Brizzi, A, de Novellis, V, Marabese, I, Ross, R, van de Doelen, T, Brizzi, V, Pertwee, R, Maione, S, Di Marzo, V
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2006
Aiheet:
Research Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978428/
https://ncbi.nlm.nih.gov/pubmed/16953186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706888
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